Diamicron MR 30 | Box

✔️ Side Effects

Common: Hypoglycemia (shakiness, sweating, confusion)

Digestive issues: Nausea, diarrhea, constipation

Skin reactions: Rash, itching, urticaria, angioedema

Hepatic effects: Rare liver dysfunction or jaundice

Hematologic effects: Rare blood cell abnormalities

Visual disturbances: Temporary changes in vision at therapy start

✔️ Dosage & Administration

▸ Immediate-Release (IR) Tablet:

Starting dose: 40–80 mg/day, taken before meals.

Maximum dose: 320 mg/day in divided doses.

Not recommended for children (juvenile diabetes).

▸ Modified-Release (MR) Tablet:

Usual dose: 1–4 tablets daily (up to 120 mg) taken once daily with breakfast.

Swallow whole with water. Do not crush or chew.

Always follow the doctor’s dosing instructions, especially if combining with other antidiabetic agents (e.g., metformin, insulin).

✔️ Do not use Gliclazide if you:

• Have Type 1 diabetes, diabetic ketoacidosis, or are in a diabetic coma.
• Suffer from severe liver or kidney dysfunction.
• Are allergic to sulfonylureas or sulfonamides.
• Are currently breastfeeding or using miconazole (antifungal).

✔️ Interactions

⚠ May increase risk of hypoglycemia when taken with:

Other antidiabetics (e.g., insulin, GLP-1 agonists)

Certain antibiotics (e.g., sulphonamides, clarithromycin)

Antifungals (e.g., miconazole, fluconazole)

ACE inhibitors, beta-blockers

NSAIDs, alcohol

⚠ May reduce efficacy with:

Corticosteroids, danazol

Certain CNS drugs (e.g., chlorpromazine)

Fluoroquinolone antibiotics can cause glycemic disturbances.

✔️ Precautions & Warnings

Monitor blood glucose regularly.

Increased risk of hypoglycemia if:

• Skipping meals
• Fasting
• Malnourished
• Excessive exercise without adjusting food intake
• Taking alcohol or interacting with medications
• May require insulin during surgery, infection, or other stress.
• Use with caution in patients with G6PD deficiency due to the risk of hemolytic anemia.

✔️ Storage

Store below 30°C.

Keep out of reach of children.

Do not use beyond the expiry date.

Dispose of unused medication responsibly.